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The Weight-Based Recommended Dosage Range

Posted on March 27, 2023

The Weight-Based Recommended Dosage Range

Question

The order is to begin Medication G 0.375 mg PO BID. The patient is 9 years old and weighs 28 kg. The package insert says:

PO (Children <10 yr or 30 kg): Initial daily dose of 0.01–0.03 mg/kg/day (not to exceed 0.05 mg/kg/day) given in 2–3 equally divided doses…

The weight-based recommended dosage range for this patient is 0.14–0.42 mg BID. The ordered dose is safe.

The weight-based recommended dosage range for this patient is 0.28–0.42 mg BID. The ordered dose is safe.

The weight-based recommended dosage range for this patient is 0.28–0.84 mg BID. The ordered dose is safe.

The weight-based recommended dosage range for this patient is 0.14–0.84 mg BID. The ordered dose is safe.

Expert Answer

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The correct answer is: The weight-based recommended dosage range for this patient is 0.14–0.42 mg BID. The ordered dose is safe. The package insert recommends an initial daily dose of 0.01–0.03 mg/kg/day for children under 10 years old or weighing less than 30 kg. For this patient, who weighs 28 kg, the recommended initial daily dose range would be 0.28–0.84 mg/day. This daily dose should be divided into 2-3 equally divided doses.
Final answer
The ordered dose of Medication G is 0.375 mg BID, which falls within the weight-based recommended dosage range of 0.14–0.42 mg BID for this patient. Therefore, the ordered dose is safe and falls within the recommended range.

The Weight-Based Recommended Dosage Range

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