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Reducing The Number Of Fractions Discussion Paper

Posted on April 6, 2023

Reducing The Number Of Fractions Discussion Paper

A lung patient is planned to receive 45 Gy in 25 fractions at 1.8 Gy/fx. Due to scheduling issues, the physician would like to reduce the number of fractions to 17 while keeping the same biological effect on the tumor. What fraction size and total dose will give the same effect to tumor?

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Step 1/2
Total radiation dose planned – 45Gy in 25 fractions
dose given per fraction- 45/25=1.8 Gy
to keep the same effect on tumour, total dose will remail the same
Step 2/2
Now, total dose planned is 45 Gy, and number of fractions is 17
so, dose per fraction= 45/17=2.64 Gy/fraction
but, maximum dose of rdiotherapy to avoid serious complications like pneumonitis, max dose per fraction is 2Gy.
Final answer
So, fraction size of 2Gy per fraction, and total 17 fractions, total dose given will be 34 Gy. Reducing The Number Of Fractions Discussion Paper

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