Prevention Of Myocardial And Cerebral Infarction Discussion
Aspirin is considered as an acidic drug given at a dose of 80 mg tablet as an antithrombotic agent for patients with angina and prevention of myocardial and cerebral infarction. In today’s market, some preparations of aspirin would be given as 100 mg enteric coated tablet. Rationalize the need to enteric coat the aspirin tablet.
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Aspirin, also known as acetylsalicylic acid, is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used for its analgesic, antipyretic, and anti-inflammatory properties. Aspirin works by inhibiting the synthesis of prostaglandins, which are involved in inflammation, pain, and fever.
However, aspirin can also cause gastrointestinal (GI) side effects, such as gastric irritation, ulceration, and bleeding, due to its acidic nature. The acidic properties of aspirin can damage the lining of the stomach and intestines, leading to discomfort, pain, and bleeding.
To prevent these side effects, some preparations of aspirin are enteric-coated. Enteric coating is a special coating that is designed to resist the acidic environment of the stomach and dissolve in the alkaline environment of the small intestine. This means that the aspirin tablet can bypass the stomach and release the active ingredient in the small intestine, reducing the risk of GI side effects.
In the case of the 100 mg enteric-coated aspirin tablet, the enteric coating allows for the drug to be absorbed in the small intestine and provides a more targeted delivery of the drug to the bloodstream. This can be particularly beneficial for patients who are at risk of GI complications or who have a history of GI problems.
In summary, enteric coating of aspirin tablets helps to reduce the risk of GI side effects and improve the efficacy of the drug. Prevention Of Myocardial And Cerebral Infarction Discussion