Research and describe the underlying causes for the elevated levels of any one of the liver enzymes described in a liver function test.
A liver function test is a blood test that measures the levels of various liver enzymes, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT), among others. Elevated levels of these enzymes can indicate liver damage or disease. Important of Liver Function Test Essay Sample
All of the liver enzymes measured in a liver function test, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT), provide important information about liver health and function but since ALT is more specific to liver hence it should be given preference.
Alanine aminotransferase (ALT) is a liver enzyme that is involved in liver metabolism. It is primarily found in liver cells, and its main function is to catalyze the transfer of an amino group from alanine to alpha-ketoglutarate, producing pyruvate and glutamate.
In a liver function test, elevated levels of ALT in the bloodstream can indicate liver damage or disease. ALT levels can be elevated when liver cells are damaged and release the enzyme into the bloodstream. Elevated ALT levels can occur in a variety of liver conditions, including:
- Viral hepatitis: Inflammation of the liver caused by a viral infection can cause liver cells to become damaged and release increased levels of ALT into the bloodstream.
- Liver cirrhosis: Scarring of the liver that can result from chronic liver disease, such as alcoholism or nonalcoholic fatty liver disease, can cause the liver cells to become damaged and release increased levels of ALT.
- Acetaminophen overdose: Overdose of the pain reliever acetaminophen can cause liver damage and elevated levels of ALT.
- Fatty liver disease: Accumulation of fat in the liver can cause liver cells to become damaged and release increased levels of ALT.
- Alcoholic liver disease: Chronic alcohol consumption can cause liver damage and elevated levels of ALT.
Hence we conclude that AST (Aspartate Aminotransferase) is an important liver enzyme because it provides important information about the health of the liver. Elevated levels of AST can indicate liver damage, inflammation, or disease, such as hepatitis, cirrhosis, or liver cell injury. Measuring the levels of AST in the blood is a common way to assess liver function and monitor the progression of liver disease. AST is also used in combination with other liver tests, such as ALT (Alanine Aminotransferase) and ALP (Alkaline Phosphatase), to diagnose and monitor liver conditions. Important of Liver Function Test Essay Sample