Anti-inflammatory and Antigout Drugs Essay Paper
Chapter 44: Anti-inflammatory and Antigout Drugs (Group # 2)
A.R. is a 66-year-old male patient who comes to the clinic today with complaints of a painful big toe. Upon examination, the nurse notes that the toe is very red and swollen at the joint. A.R. advises the nurse not to touch his toe because it hurts so badly that he “cannot even wear a sock.” The nurse notes a significant decrease in the mobility of the big toe as well. A.R. has a history of ulcers, and the nurse notes that he consumes “several” alcoholic beverages each day. The physician sends A.R. to the laboratory for a uric acid level, and the results demonstrate a significant elevation. The physician makes a diagnosis of gouty arthritis and gives A.R. a prescription for febuxostat (Uloric) and colchicine.
1. What is the mechanism of action of colchicine, and how will this drug help A.R.?
2. What is the mechanism of action of febuxostat, and how will this drug help A.R.?
3. What side effects of febuxostat will the nurse teach the patient about?